[News] Hidradenitis Suppurativa comparing oral antibiotics & antiandrogen therapy

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Hidradenitis  suppurativa in 64 female patients: retrospective study 
comparing oral  antibiotics and antiandrogen therapy.

J Cutan Med Surg. 2007  Jul-Aug;11(4):125-31

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractP
lus&list_uids=17601419&itool=pubmed_DocSum

or  

http://preview.tinyurl.com/287ra4

The study attempted to  determine the success rate for a variety of 
treatments in female Hidradenitis  Suppurativa (HS) patients and whether 
androgen-related tests can predict a  response to antiandrogen therapy.  It also attempted 
to determine if it is  associated with Polycystic Ovary Syndrome (PCOS).  The 
study was performed  using a retrospective chart review.  It found antiandrogen 
therapy was  superior to oral antibiotic therapy.  Sixty four (64) women were 
included  in the study.  Twenty one (21) were found to have androgen excess 
which  equates to 32.8%.  Eight (8) out of the 21 women (38.1%) with androgen  
excess had PCOS.  This equated to a higher than expected prevalence of  PCOS.  
The study concluded that a hormonal manipulation approach to therapy  should 
be considered in all women presenting with HS. Female patients presenting  
with HS should prompt investigations for underlying PCOS and insulin resistance.  
 




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