From news at lists.pcolist.org Tue Jul 3 23:15:40 2007 From: news at lists.pcolist.org (news@lists.pcolist.org) Date: Fri Jul 6 00:19:45 2007 Subject: [News] Low serum 25-hydroxyvitamin D associated with IR and obesity in women with PCOS Message-ID: Please copy and paste the entire link which may be more than one line long or the shorter tiny URL link in your browser's address bar. _________________________________________ Low serum 25-hydroxyvitamin D concentrations are associated with insulin resistance and obesity in women with polycystic ovary syndrome. Exp Clin Endocrinol Diabetes. 2006 Nov;114(10):577-83 The aim of this study was to investigate the effect of 25-hydroxyvitamin D (25-OH-VD) on metabolic parameters and IR in PCOS. Women with hypovitaminosis D (<9 ng/ml) had higher mean BMI, indices of IR and leptin levels compared to women with normal serum levels. The study concluded that in PCOS women, low 25-OH-VD levels are associated with obesity and insulin resistance but not with PCOS per se. ************************************** See what's free at http://www.aol.com. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://lists.pcolist.org/pipermail/news/attachments/20070703/7e15297d/attachment.html From news at lists.pcolist.org Fri Jul 6 00:11:25 2007 From: news at lists.pcolist.org (news@lists.pcolist.org) Date: Sat Jul 7 19:50:47 2007 Subject: [News] Abdominal fat quantity & distribution in women with PCOS & relationship to IR Message-ID: Please copy and paste the entire link which may be more than one line long or the shorter tiny URL link in your browser's address bar. ___________________________________________ ABDOMINAL FAT QUANTITY AND DISTRIBUTION IN WOMEN WITH POLYCYSTIC OVARY SYNDROME AND EXTENT OF ITS RELATION TO INSULIN RESISTANCE. J Clin Endocrinol Metab. 2007 Apr 3 http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractP lus&list_uids=17405838&itool=pubmed_DocSum or http://preview.tinyurl.com/2uppj5 Increased abdominal fat has been linked to insulin resistance and increased cardiovascular risk. Because many patients with PCOS present abdominal obesity, it may be the cause of insulin resistance in this disorder. One hundred ten patients with PCOS and one hundred twelve weight matched controls were studied. PCOS patients with increased central abdominal fat had significantly higher insulin levels and significantly reduced insulin sensitivity than controls with similar quantities of central abdominal fat. Overweight PCOS patients with normal abdominal fat had significantly higher insulin levels and significantly reduced insulin sensitivity than overweight controls with normal abdominal fat. ************************************** See what's free at http://www.aol.com. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://lists.pcolist.org/pipermail/news/attachments/20070706/e56df396/attachment.html From news at lists.pcolist.org Sat Jul 7 19:42:07 2007 From: news at lists.pcolist.org (news@lists.pcolist.org) Date: Wed Jul 18 00:50:05 2007 Subject: [News] Hidradenitis Suppurativa comparing oral antibiotics & antiandrogen therapy Message-ID: Please copy and paste the entire link which may be more than one line long or the shorter tiny URL link in your browser's address bar. __________________________________ Hidradenitis suppurativa in 64 female patients: retrospective study comparing oral antibiotics and antiandrogen therapy. J Cutan Med Surg. 2007 Jul-Aug;11(4):125-31 http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractP lus&list_uids=17601419&itool=pubmed_DocSum or http://preview.tinyurl.com/287ra4 The study attempted to determine the success rate for a variety of treatments in female Hidradenitis Suppurativa (HS) patients and whether androgen-related tests can predict a response to antiandrogen therapy. It also attempted to determine if it is associated with Polycystic Ovary Syndrome (PCOS). The study was performed using a retrospective chart review. It found antiandrogen therapy was superior to oral antibiotic therapy. Sixty four (64) women were included in the study. Twenty one (21) were found to have androgen excess which equates to 32.8%. Eight (8) out of the 21 women (38.1%) with androgen excess had PCOS. This equated to a higher than expected prevalence of PCOS. The study concluded that a hormonal manipulation approach to therapy should be considered in all women presenting with HS. Female patients presenting with HS should prompt investigations for underlying PCOS and insulin resistance. ************************************** See what's free at http://www.aol.com. From news at lists.pcolist.org Wed Jul 18 00:43:04 2007 From: news at lists.pcolist.org (news@lists.pcolist.org) Date: Sat Jul 21 03:47:55 2007 Subject: [News] Increased risk of depressive disorders in women with polycystic ovary syndrome. Message-ID: Please copy and paste the entire link which may be more than one line long or the shorter tiny URL link in your browser's address bar. __________________________________________ Increased risk of depressive disorders in women with polycystic ovary syndrome. Fertil Steril. 2007 Jun;87(6):1369-76 http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractP lus&list_uids=17397839&itool=pubmed_DocSum or http://preview.tinyurl.com/2jjg4e The goals of this study were to estimate the prevalence of depressive disorders in women with PCOS compared with controls and to evaluate the correlation between depression, hyperandrogenism, and other metabolic markers. Women with PCOS were at an increased risk for depressive disorders (new cases) compared with controls (21% vs. 3%). Compared with the non-depressed PCOS subjects, the depressed PCOS subjects had a higher body mass index (BMI) and evidence of insulin resistance. The study concluded that there is a significantly increased risk of depressive disorders in women with PCOS and recommend routine screening in this population. ************************************** Get a sneak peek of the all-new AOL at http://discover.aol.com/memed/aolcom30tour -------------- next part -------------- An HTML attachment was scrubbed... URL: http://lists.pcolist.org/pipermail/news/attachments/20070718/2f426407/attachment.html From news at lists.pcolist.org Sat Jul 21 03:48:44 2007 From: news at lists.pcolist.org (news@lists.pcolist.org) Date: Tue Aug 21 02:10:26 2007 Subject: [News] Polycystic ovary syndrome in men: Stein-Leventhal syndrome revisited. Message-ID: Please copy and paste the entire link which may be more than one line long or the shorter tiny URL link in your browser's address bar. __________________________________ Polycystic ovary syndrome in men: Stein-Leventhal syndrome revisited. Med Hypotheses. 2007;68(3):480-3 http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractP lus&list_uids=17134841&itool=pubmed_DocSum or http://preview.tinyurl.com/yuxa2v Polycystic ovary syndrome (PCOS), also referred to as Stein-Leventhal syndrome, is characterized by hyperandrogenism, hyperinsulinemia, central obesity, polycystic ovaries, and anovulation. However, some of these manifestations, including the polycystic ovaries, are neither specific for the disorder, nor found in all affected individuals. Since the primary defect underlying PCOS may be an upstream endocrine and/or metabolic disturbance, rather than a defect in the ovaries themselves, this study hypothesizes that this aberration can also arise in men and that the absence of polycystic ovaries in men with other stigmata of the disorder should not eliminate the diagnosis. Recognition of this syndrome in men is important, since pharmacologic treatments identified for women with PCOS may alleviate metabolic problems related to insulin resistance and its sequelae in men with a similar underlying defect. This study suggests that first-degree relatives of patients with PCOS should be examined not only for phenotypic features characteristic of PCOS but also for biochemical evidence of hyperinsulinemia and hyperandrogenism. In addition to examining these individuals for obesity, the women should be evaluated for hirsutism and the men should be screened for early-onset male-pattern alopecia and excess hairiness. As new treatments for PCOS emerge, e.g. insulin-sensitizing drugs, it will be important to determine if these treatments have beneficial effects on the metabolic symptoms and complications in all afflicted patients, regardless of gender. ************************************** Get a sneak peek of the all-new AOL at http://discover.aol.com/memed/aolcom30tour -------------- next part -------------- An HTML attachment was scrubbed... URL: http://lists.pcolist.org/pipermail/news/attachments/20070721/4b3833c8/attachment.html