[News] Searching for PCOS in postmenopausal women: evidence of association with CVD

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Searching for polycystic  ovary syndrome in postmenopausal women: evidence of 
a dose-effect association  with prevalent cardiovascular disease.

Menopause. 2007 Jan 19

The  objective of this study was to test the hypothesis that PCOS is 
associated with  an increased risk of arteriosclerotic cardiovascular disease (CVD).   
 The study involved 713 non-estrogen using postmenopausal white women who 
were  between 65 and 82 years old and with a BMI between 21.5 and 27.5.  The PCOS 
 phenotype was found in 9.3% of the women and 5.8% of the non-diabetic  
women.   The prevalence of CVD was similar between women with and  without PCOS.   
Among women with intact ovaries and no diabetes, there  was a stepwise graded 
association between an increasing number of features of  the PCOS phenotype 
(ie, none to three or more) and prevalent CVD.  A  similar association was also 
observed for coronary heart disease alone.  

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