[News] The frequency and characteristics of insulin resistance in women with PCOS

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The frequency of insulin  resistance calculated upon the basis of a fasting 
glucose to insulin ratio and  characteristics of insulin resistant women with 
polycystic ovary  syndrome.

Prilozi.  2006;27(1):87-95

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abst
ractPlus&list_uids=16985482&itool=pubmed_DocSum

This  study attempted to calculate the frequency of inuslin resistance in 
women with  PCOS.  It was found that 58.06% of women with PCOS and with a BMI 
greater  than or equal to 25 (overweight or obese) were insulin resistant.  The 
sex  hormone binding globulin (SHBG) were significantly lower in the insulin  
resistant group and they had a higher free testosterone index.   Progesterone 
levels were lower in the insulin resistance group. The study  concluded that 
the fasting glucose to insulin ratio is a simple and useful test  for 
identifying insulin-resistant obese women with PCOS.  By using that,  the women with 
PCOS who would benefit from therapy with insulin sensitizers can  be identified.