[News] The impact of obesity on reproduction in women with polycystic ovary syndrome

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The impact of  obesity on reproduction in women with polycystic ovary syndrome

BJOG: An  International Journal of Obstetrics &  Gynaecology

http://www.blackwell-synergy.com/doi/abs/10.1111/j.1471-0528.2006.00990.x

Compared  with normal weight women with PCOS, those with obesity are 
characterized by a  worsened hyperandrogenic and metabolic state, poorer menses and 
ovulatory  performance and, ultimately, poorer pregnancy rates.  The importance 
of  obesity in the pathogenesis of PCOS is emphasized by the efficacy of 
lifestyle  intervention and weight loss, not only on metabolic alterations but also 
on  hyperandrogenism, ovulation and fertility.  The increasing prevalence of  
obesity among adolescent and young women with PCOS may partly depend on the  
increasing worldwide epidemic of obesity, although this hypothesis should be  
supported by long-term prospective epidemiological trials.